--- title: "Syphilis Test: What It Screens For | AMH Nationwide" description: "Learn syphilis test what it screens for including specific antibodies and infection stages. Call (877) 731-6362 for lab testing and panel options." author: "AMH Nationwide" date: "2026-08-27" tags: ["syphilis test what it screens"] canonical: "https://amhnationwide.com/syphilis-test-what-it-screens/" last_updated: "2026-08-27" --- # Syphilis Test: What It Screens For | AMH Nationwide **By AMH Nationwide** | August 27, 2026 Learn syphilis test what it screens for including specific antibodies and infection stages. Call (877) 731-6362 for lab testing and panel options. --- Syphilis test what it screens includes detection of antibodies to Treponema pallidum, the bacterium causing syphilis. This test identifies active or past infection stages depending on the panel. AMH Nationwide routes samples through five national labs. Call (877) 731-6362 to arrange testing. OVERVIEW ## What does a syphilis test screen for? A syphilis test screens for antibodies produced in response to the bacterium Treponema pallidum, which causes syphilis. The test detects markers that indicate current or past infection. Depending on the panel, it may include non-treponemal tests like RPR or VDRL, and treponemal tests such as FTA-ABS or TP-PA. TEST PANELS ## How does the panel size affect what a syphilis test screens? The panel size determines the number and type of antibodies detected in a syphilis test. Smaller panels may screen only with a non-treponemal test, which detects active infection but can produce false positives. Larger panels combine non-treponemal and treponemal tests, improving specificity and confirming diagnosis. Small Panel: Non-treponemal test (RPR or VDRL) only Medium Panel: Non-treponemal plus one treponemal test (FTA-ABS or TP-PA) Comprehensive Panel: Multiple treponemal tests plus non-treponemal tests for confirmation LAB NETWORKS ## Which labs process syphilis tests ordered through AMH Nationwide? AMH Nationwide routes syphilis test specimens through five national lab networks: [Quest Diagnostics](https://www.questdiagnostics.com/), [LabCorp](https://www.labcorp.com/), Omega Labs, United States Drug Testing Labs, and ExperTox. Each lab follows strict protocols to ensure accurate detection of syphilis antibodies. COLLECTION & ORDERING ## How is a syphilis test collected and ordered? AMH Nationwide provides the lab order and directs the requester to a nearby collection site within the national lab networks. Syphilis testing requires blood samples collected by trained personnel. There is no online ordering; to arrange testing, call (877) 731-6362. ## Arrange Your Syphilis Test Today To schedule syphilis testing or discuss panel options, call (877) 731-6362. AMH Nationwide will direct you to a certified collection site within our national lab networks. [Call (877) 731-6362](tel:+18777316362)[Contact Us](https://amhnationwide.com/contact-us/) RESULTS & REVIEW ## How are syphilis test results reviewed and reported? All non-negative syphilis test results undergo review by a certified Medical Review Officer (MRO) as part of standard processing. This ensures accurate interpretation of antibody presence and infection status. Results are reported confidentially to the requester. ADDITIONAL INFO ## Does the syphilis test detect all stages of infection? Yes, depending on the panel, the syphilis test can detect antibodies present in primary, secondary, latent, and tertiary stages of infection. Non-treponemal tests detect active infection, while treponemal tests may remain positive for life, indicating past or treated infection. AMH Reviewed & Maintained By AMH Nationwide Customer Service AMH Nationwide is BBB A+ accredited and routes every order through Quest Diagnostics, LabCorp, Omega Labs, United States Drug Testing Labs, or ExperTox, all of which use multiple lab certification agencies and standards such as [SAMHSA](https://www.samhsa.gov/workplace/drug-testing)-aligned laboratory protocols, the ANSI National Accreditation Board for forensic testing and calibration, the College of American Pathologists (CAP), and Clinical Laboratory Improvement Amendments (CLIA). Every non-negative screen is reviewed by a certified Medical Review Officer as part of standard processing before a result is released, and chain-of-custody documentation is maintained on every collection. This page does not constitute medical or legal advice. **Last updated:** July 2026 You May Also Need [Nail Drug TestingNo head or body hair available? A 5-panel fingernail test covers a similar look-back window.Learn more →](https://amhnationwide.com/5-panel-fingernail-drug-test/)[ChildGuard: Environmental ExposureConcerned about a child or loved one? ChildGuard screens for exposure to drugs in their environment.Learn more →](https://amhnationwide.com/5-panel-hair-drug-test-environmental-exposure-childguard/)[Shorten the Detection WindowShortened options like 30 and 60 day hair panels are also available, useful when a urine test’s 1-3 day window is too short.Learn more →](https://amhnationwide.com/30-day-hair-drug-test/)[Hair ETG Alcohol TestAlso need alcohol testing? The hair ETG test screens for alcohol use, and can be added to the same collection.Learn more →](https://amhnationwide.com/etg-and-peth/) Frequently Asked Questions ## Common Questions Syphilis tests detect antibodies against Treponema pallidum. Non-treponemal tests identify antibodies to cardiolipin, indicating active infection, while treponemal tests detect antibodies specific to the bacterium itself. Yes, non-treponemal tests can detect early active infection usually within weeks of exposure, while treponemal tests confirm infection but may take longer to become positive. Yes, AMH Nationwide routes specimens through Quest Diagnostics, LabCorp, Omega Labs, United States Drug Testing Labs, and ExperTox, ensuring broad access to testing. Larger panels combining non-treponemal and treponemal tests improve accuracy by confirming true positives and reducing false positives compared to smaller panels with only one test type. All non-negative results are reviewed by a certified Medical Review Officer to verify findings and ensure proper interpretation before reporting. Call (877) 731-6362 to obtain a lab order and be directed to a collection site. AMH Nationwide does not offer online ordering. Sources • [SAMHSA – Mandatory Guidelines for Federal Workplace Drug Testing Programs](https://www.samhsa.gov/workplace/drug-testing) • [U.S. DOT – 49 CFR Part 40 – Procedures for Transportation Workplace Drug and Alcohol Testing Programs](https://www.transportation.gov/odapc/part40) • [CDC – National Center for Health Statistics – Drug Use FastStats](https://www.cdc.gov/nchs/fastats/drug-use.htm) • [Quest Diagnostics – Employer Solutions, Hair Testing Methodology](https://www.questdiagnostics.com/) • [LabCorp – Occupational Testing Services](https://www.labcorp.com/) ## Ready to get started? AMH Nationwide provides the lab order and arranges collection nationwide. Every non-negative result reviewed by a certified Medical Review Officer. Call (877) 731-6362 or contact us. [Call (877) 731-6362](tel:+18777316362)[Contact Us](https://amhnationwide.com/contact-us/) --- **Need a drug, alcohol, HIV or STD test?** AMH Nationwide is a national lab testing agency operating since 2004, with more than 20,000 collection sites across the United States. Hair, urine, fingernail and blood testing, panels from 5 through 19, for individuals and employers. - Call: (877) 731-6377 - Find a collection site: https://amhnationwide.com/locations/ - Full page: https://amhnationwide.com/syphilis-test-what-it-screens/